Homer Simpson's classic D'oh sound effect from The Simpsons, used when something goes wrong in memes, edits and reaction videos for comic fails.
The clip is Homer Simpson's instantly recognisable D'oh, a short, frustrated groan that drops in pitch as he realises he has made a mistake. Voiced in a deep, exasperated tone, it starts with a sharp burst and trails off into a defeated sigh, packing embarrassment, annoyance and self-blame into less than a second. Because almost everyone knows the character and the catchphrase, the sound lands immediately without any explanation, turning a small slip, a failed attempt or an awkward moment into a punchline. It feels warm and familiar rather than harsh, which is why it works so well as a quick reaction.
D'oh is the signature exclamation of Homer Simpson, the father at the centre of The Simpsons, the long-running American animated sitcom that first aired in 1989. Homer utters it whenever his plans backfire, he says the wrong thing, or he injures himself through his own carelessness, and the word quickly became shorthand for comic frustration. Repeated across decades of episodes, clips and online memes, it moved far beyond the show itself, and creators still reach for it because a single syllable instantly tells viewers that something has gone hilariously wrong.